Title

Rosenthal Fibers and Eosinophilic Granular Bodies in a Classic Acoustic Schwannoma.

Publication/Presentation Date

11-1-1997

Abstract

We describe unique features seen in a case of classic acoustic schwannoma. In the central portion of the tumor, abundant Rosenthal fibers and occasional eosinophilic granular bodies were present. Rosenthal fibers are homogeneous eosinophilic structures commonly seen in central nervous system lesions, such as pilocytic astrocytoma, or in the gliotic tissues adjacent to slowly growing neoplasms and some congenital malformations. Eosinophilic granular bodies are also structural markers of slow-growing, well-differentiated neuroglial neoplasms, such as pleomorphic xanthoastrocytoma, ganglion cell tumors, and pilocytic astrocytoma. To the best of our knowledge, however, these two structures have never before been described in schwannomas.

Volume

121

Issue

11

First Page

1207

Last Page

1209

ISSN

0003-9985

Disciplines

Medical Pathology | Pathology

PubMedID

9372750

Department(s)

Department of Pathology and Laboratory Medicine, Pathology Laboratory Medicine Faculty

Document Type

Article