Title

Acanthosis nigricans, vitamin D, and insulin resistance in obese children and adolescents.

Publication/Presentation Date

11-1-2014

Abstract

OBJECTIVES: The aim of this study is to identify factors accounting for the variation in 25-hydroxyvitamin D levels in a pediatric obese population.

PATIENTS AND METHODS: One hundred and forty-nine obese children and adolescents (BMI ≥95th percentile) were evaluated in a pediatric endocrine office. Acanthosis nigricans (AN) skin lesions were rated on a 4-point scale.

RESULTS: The 25-hydroxyvitamin D levels were significantly different between those without AN and those with any severity of AN (p=

CONCLUSIONS: Season of evaluation was the main determinant of 25-hydroxyvitamin D levels. Severity of AN was a stronger predictor of 25-hydroxyvitamin D level variation than the measure of insulin resistance HOMA-IR.

Volume

27

Issue

11-12

First Page

1107

Last Page

1111

ISSN

2191-0251

Disciplines

Medicine and Health Sciences | Pediatrics

PubMedID

25010776

Department(s)

Department of Pediatrics, Department of Pediatrics Faculty, Department of Pediatrics Residents

Document Type

Article