Metronidazole vs. Erythromycin, Neomycin, and Cefazolin in Prophylaxis for Colonic Surgery.
Publication/Presentation Date
1-1-1989
Abstract
A prospective, double-blind, randomized study was undertaken to compare perioperative parenteral metronidazole and erythromycin, One neomycin, and cefazolinhundred fifty-five patients were randomized into two groups by the pharmacy department. The resulting difference between the overall septic complication rate in patients receiving erythromycin, neomycin, and cefazolin (10.9 percent) and the rate in patients receiving metronidazole alone (31.9 percent) was significant. This indicates that an antibiotic to cover aerobic bacteria should be added to the regimen when metronidazole is used.
Volume
32
Issue
1
First Page
17
Last Page
20
ISSN
0012-3706
Published In/Presented At
Khubchandani, I. T., Karamchandani, M. C., Sheets, J. A., Stasik, J. J., Rosen, L., & Riether, R. D. (1989). Metronidazole vs. erythromycin, neomycin, and cefazolin in prophylaxis for colonic surgery. Diseases Of The Colon And Rectum, 32(1), 17-20.
Disciplines
Other Medical Specialties | Surgery
PubMedID
2910656
Department(s)
Department of Surgery, Department of Surgery Faculty
Document Type
Article