Aging and loss to follow-up among youth living with human immunodeficiency virus in the HIV Research Network.
Publication/Presentation Date
3-1-2015
Abstract
PURPOSE: In the United States, 21 years is a critical age of legal and social transition, with changes in social programs such as public insurance coverage. Human immunodeficiency virus (HIV)-infected youth have lower adherence to care and medications and may be at risk of loss to follow-up (LTFU) at this benchmark age. We evaluated LTFU after the 22nd birthday for HIV-infected youth engaged in care. LTFU was defined as having no primary HIV visits in the year after the 22nd birthday.
METHODS: All HIV-infected 21-year-olds engaged in care (2002-2011) at the HIV Research Network clinics were included. We assessed the proportion LTFU and used multivariable logistic regression to evaluate demographic and clinical characteristics associated with LTFU after the 22nd birthday. We compared LTFU at other age transitions during the adolescent/young adult years.
RESULTS: Six hundred forty-seven 21-year-olds were engaged in care; 91 (19.8%) were LTFU in the year after turning 22 years. Receiving care at an adult versus pediatric HIV clinic (adjusted odds ratio [AOR], 2.91; 95% confidence interval [CI], 1.42-5.93), having fewer than four primary HIV visits/year (AOR, 2.72; 95% CI, 1.67-4.42), and antiretroviral therapy prescription (AOR, .50; 95% CI, .41-.60) were independently associated with LTFU. LTFU was prevalent at each age transition, with factors associated with LTFU similar to that identified for 21-year-olds.
CONCLUSIONS: Although 19.8% of 21-year-olds at the HIV Research Network sites were LTFU after their 22nd birthday, significant proportions of youth of all ages were LTFU. Fewer than four primary HIV care visits/year, receiving care at adult clinics and not prescribed antiretroviral therapy, were associated with LTFU and may inform targeted interventions to reduce LTFU for these vulnerable patients.
Volume
56
Issue
3
First Page
345
Last Page
351
ISSN
1879-1972
Published In/Presented At
Agwu, A. L., Lee, L., Fleishman, J. A., Voss, C., Yehia, B. R., Althoff, K. N., Rutstein, R., Mathews, W. C., Nijhawan, A., Moore, R. D., Gaur, A. H., & Gebo, K. A. (2015). Aging and loss to follow-up among youth living with human immunodeficiency virus in the HIV Research Network. The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 56(3), 345–351. https://doi.org/10.1016/j.jadohealth.2014.11.009
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
25703322
Department(s)
Administration and Leadership
Document Type
Article