Tricyclic Antidepressant Toxicity Treated With Massive Sodium Bicarbonate
Tricyclic antidepressant (TCA) morbitity is primarily due to cardiac arrhythmias and hypotension, which become more refractory to treatment as acidosis progresses (Ann Emerg Med. 1985;14:1-9; Clin Toxicol. 2007;45:203-233; Flomenbaum N, Goldfrank L, Hoffman R, et al. Goldfrank's toxicologic emergencies. 8th ed. McGraw-Hill Companies, Inc, 2006). Early recognition and aggressive treatment are necessary for patient survival.
Published In/Presented At
Pierog, J. E., Kane, K. E., Kane, B. G., Donovan, J. W., & Helmick, T. (2009). Tricyclic antidepressant toxicity treated with massive sodium bicarbonate. The American Journal Of Emergency Medicine, 27(9), 1168.e3-7. doi:10.1016/j.ajem.2008.11.026.
Emergency Medicine | Medical Specialties | Medicine and Health Sciences
Department of Emergency Medicine, Department of Emergency Medicine Faculty, Department of Emergency Medicine Residents