The predictive value of liver tests for the presence of liver metastases.
Publication/Presentation Date
9-1-2023
Abstract
AIM: To analyze the predictive value of biochemical liver tests in patients with malignant melanoma, breast, colorectal or lung cancers at the time of diagnosis of liver metastases.
METHODS: A retrospective review of patients with the above-mentioned solid tumors at MedStar Georgetown University Hospital from 2016-2020.
RESULTS: The highest optimal cutoff according to sensitivity and specificity for the presence of liver metastases was for AST ≥1.5 × ULN for melanoma, lung, and breast cancers and ≥2 × ULN for colorectal cancer, ALT ≥1.25 × ULN for melanoma, breast and colorectal cancers and ≥1.5 × ULN for lung cancer, and ALP ≥1.5 × ULN for melanoma, breast and colorectal cancers.
CONCLUSION: Using thresholds of liver enzymes above the ULN may improve the diagnostic accuracy for the presence of liver metastases.
Volume
10
Issue
3
First Page
48
Last Page
48
ISSN
2045-0923
Published In/Presented At
Kimchy, A. V., Singh, H., Parikh, E., Rosenberg, J., Sanghavi, K., & Lewis, J. H. (2023). The predictive value of liver tests for the presence of liver metastases. Hepatic oncology, 10(3), HEP48. https://doi.org/10.2217/hep-2023-0003
Disciplines
Medicine and Health Sciences
PubMedID
37885607
Department(s)
Fellows and Residents
Document Type
Article