A Database Developed with Information Extracted from Chemotherapy Drug Package Inserts to Enhance Future Prescriptions.

Publication/Presentation Date

1-1-2011

Abstract

Package inserts of Food and Drug Administration (FDA) approved prescription drugs, including chemotherapy drugs, must follow a specific format imposed by the FDA. These inserts are created by unrelated pharmaceutical companies and as a result tend to be very different in the way the required information is reported. Chemical and pharmacokinetic properties including absorption, distribution, metabolism, excretion, and toxicity (ADME/Tox) are crucial elements to a prescribing information packet and are often missing from the reported data. This undergraduate research project analyzes the information packets of 85 randomly chosen chemically diverse chemotherapy drugs for four parameters important to patient care; viz, volume of distribution (V

Volume

2011

First Page

219

Last Page

226

ISSN

2160-7508

Disciplines

Medicine and Health Sciences

PubMedID

25302340

Department(s)

Hematology-Medical Oncology Division

Document Type

Article

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