The Salivary Mycobiome Contains 2 Ecologically Distinct Mycotypes.
Publication/Presentation Date
6-1-2020
Abstract
A broad range of fungi has been detected in molecular surveys of the oral mycobiome. However, knowledge is still lacking on interindividual variability of these communities and the ecologic and clinical significance of oral fungal commensals. In this cross-sectional study, we use internal transcribed spacer 1 amplicon sequencing to evaluate the salivary mycobiome in 59 subjects, 36 of whom were scheduled to receive cancer chemotherapy. Analysis of the broad population structure of fungal communities in the whole cohort identified 2 well-demarcated genus-level community types (mycotypes), with
Volume
99
Issue
6
First Page
730
Last Page
738
ISSN
1544-0591
Published In/Presented At
Hong, B. Y., Hoare, A., Cardenas, A., Dupuy, A. K., Choquette, L., Salner, A. L., Schauer, P. K., Hegde, U., Peterson, D. E., Dongari-Bagtzoglou, A., Strausbaugh, L. D., & Diaz, P. I. (2020). The Salivary Mycobiome Contains 2 Ecologically Distinct Mycotypes. Journal of dental research, 99(6), 730–738. https://doi.org/10.1177/0022034520915879
Disciplines
Medicine and Health Sciences
PubMedID
32315566
Department(s)
Department of Pathology and Laboratory Medicine
Document Type
Article