Central giant cell lesion.

Publication/Presentation Date

12-1-2011

Abstract

A classic case of central giant cell lesion (CGCL) is presented with emphasis on clinical, radiologic, and histologic features. The differential is discussed including peripheral giant cell granuloma, brown tumor of hyperparathyroidism, and giant cell tumor of bone. The molecular pathway of osteoclastogenesis is selectively reviewed and applied to suggest possible etiologies of the giant cell lesions. CGCL syndromes and treatment are also discussed.

Volume

5

Issue

4

First Page

385

Last Page

388

ISSN

1936-0568

Disciplines

Medicine and Health Sciences

PubMedID

21898170

Department(s)

Department of Pathology and Laboratory Medicine

Document Type

Article

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