Opposing Roles of Dendritic Cell Subsets in Experimental GN.
Dendritic cells (DCs) are thought to form a dendritic network across barrier surfaces and throughout organs, including the kidney, to perform an important sentinel function. However, previous studies of DC function used markers, such as CD11c or CX3CR1, that are not unique to DCs. Here, we evaluated the role of DCs in renal inflammation using a CD11c reporter mouse line and two mouse lines with DC-specific reporters,
Published In/Presented At
Brähler, S., Zinselmeyer, B. H., Raju, S., Nitschke, M., Suleiman, H., Saunders, B. T., Johnson, M. W., Böhner, A. M. C., Viehmann, S. F., Theisen, D. J., Kretzer, N. M., Briseño, C. G., Zaitsev, K., Ornatsky, O., Chang, Q., Carrero, J. A., Kopp, J. B., Artyomov, M. N., Kurts, C., Murphy, K. M., … Shaw, A. S. (2018). Opposing Roles of Dendritic Cell Subsets in Experimental GN. Journal of the American Society of Nephrology : JASN, 29(1), 138–154. https://doi.org/10.1681/ASN.2017030270
Medicine and Health Sciences
Department of Pathology and Laboratory Medicine