Aggressive Mammary Cancers Lacking Lymphocytic Infiltration Arise in Irradiated Mice and Can Be Prevented by Dietary Intervention.
Because the incidence of breast cancer increases decades after ionizing radiation exposure, aging has been implicated in the evolution of the tumor microenvironment and tumor progression. Here, we investigated radiation-induced carcinogenesis using a model in which the mammary glands of 10-month-old BALB/c mice were transplanted with
Published In/Presented At
Omene, C., Ma, L., Moore, J., Ouyang, H., Illa-Bochaca, I., Chou, W., Patel, M. S., Sebastiano, C., Demaria, S., Mao, J. H., Karagoz, K., Gatza, M. L., & Barcellos-Hoff, M. H. (2020). Aggressive Mammary Cancers Lacking Lymphocytic Infiltration Arise in Irradiated Mice and Can Be Prevented by Dietary Intervention. Cancer immunology research, 8(2), 217–229. https://doi.org/10.1158/2326-6066.CIR-19-0253
Medicine and Health Sciences
Department of Pathology and Laboratory Medicine