Convulsive and nonconvulsive status epilepticus in children.
Publication/Presentation Date
7-1-2009
Abstract
Status epilepticus (SE) is a common pediatric neurologic emergency that requires rapid assessment and management. Treatment of pediatric SE involves two equally important factors. First, rapid identification of the underlying etiology is essential, as decisions on how to treat and prognosticate depend on the cause of SE. Second, the timing of treatment initiation with adequate doses is crucial, as early action is most effective in terminating SE and decreasing morbidity and mortality. Currently, early treatment with adequate doses of a benzodiazepine is appropriate, followed by treatment with phenytoin, phenobarbital, or valproic acid. If the seizure does not stop or repetitive seizures continue, the addition of other medications (eg, levetiracetam) or pharmacologic coma induction may be indicated. This review evaluates treatment protocols for acute SE, prolonged SE, and nonconvulsive SE, including some management strategies that use newer anticonvulsants.
Volume
11
Issue
4
First Page
262
Last Page
272
ISSN
1092-8480
Published In/Presented At
Abend, N. S., & Marsh, E. (2009). Convulsive and nonconvulsive status epilepticus in children. Current treatment options in neurology, 11(4), 262–272. https://doi.org/10.1007/s11940-009-0030-8
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
19523352
Department(s)
Department of Pediatrics
Document Type
Article