Electrographic seizures and status epilepticus in critically ill children and neonates with encephalopathy.
Publication/Presentation Date
12-1-2013
Abstract
Electrographic seizures are seizures that are evident on EEG monitoring. They are common in critically ill children and neonates with acute encephalopathy. Most electrographic seizures have no associated clinical changes, and continuous EEG monitoring is necessary for identification. The effect of electrographic seizures on outcome is the focus of active investigation. Studies have shown that a high burden of electrographic seizures is associated with worsened clinical outcome after adjustment for cause and severity of brain injury, suggesting that a high burden of such seizures might independently contribute to secondary brain injury. Further research is needed to determine whether identification and management of electrographic seizures reduces secondary brain injury and improves outcome in critically ill children and neonates.
Volume
12
Issue
12
First Page
1170
Last Page
1179
ISSN
1474-4465
Published In/Presented At
Abend, N. S., Wusthoff, C. J., Goldberg, E. M., & Dlugos, D. J. (2013). Electrographic seizures and status epilepticus in critically ill children and neonates with encephalopathy. The Lancet. Neurology, 12(12), 1170–1179. https://doi.org/10.1016/S1474-4422(13)70246-1
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
24229615
Department(s)
Department of Pediatrics
Document Type
Article