Comparative study of posterior and anterior circulation stroke in childhood: Results from the International Pediatric Stroke Study.
Publication/Presentation Date
1-28-2020
Abstract
OBJECTIVE: To compare risk factors, clinical presentation, and outcomes after posterior circulation arterial ischemic stroke (PCAIS) and anterior circulation arterial ischemic stroke (ACAIS) in neonates and children.
METHODS: In this international multicenter observational study including neonates and children up to 18 years of age with arterial ischemic stroke (AIS), we compared clinical and radiologic features according to stroke location.
RESULTS: Of 2,768 AIS cases, 507 (18%) were located in the posterior circulation, 1,931 (70%) in the anterior circulation, and 330 (12%) involved both. PCAIS was less frequent in neonates compared to children (8.8% vs 22%,
CONCLUSION: PCAIS is less common than ACAIS in both neonates and children. Children with PCAIS are older and have a higher rate of CCAD, lower clinical stroke severity, and better outcome than children with ACAIS.
Volume
94
Issue
4
First Page
337
Last Page
337
ISSN
1526-632X
Published In/Presented At
Goeggel Simonetti, B., Rafay, M. F., Chung, M., Lo, W. D., Beslow, L. A., Billinghurst, L. L., Fox, C. K., Pagnamenta, A., Steinlin, M., Mackay, M. T., & IPSS Study Group (2020). Comparative study of posterior and anterior circulation stroke in childhood: Results from the International Pediatric Stroke Study. Neurology, 94(4), e337–e344. https://doi.org/10.1212/WNL.0000000000008837
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
31857436
Department(s)
Department of Pediatrics
Document Type
Article