Sickle cell disease: continuous arterial spin-labeling perfusion MR imaging in children.
Publication/Presentation Date
5-1-2003
Abstract
Cerebral blood flow (CBF) was measured with continuous arterial spin-labeling perfusion magnetic resonance (MR) imaging in 14 children with sickle cell disease and seven control subjects. Mean CBF values were higher in patients (P < .005) than in control subjects in all cerebral artery territories. Three patients had decreased CBF in right anterior and middle cerebral artery territories compared with CBF on the left, and one patient had a profound decrease in CBF in all three territories in the right hemisphere. Baseline CBF was significantly decreased in territories seen as unaffected on conventional MR images and MR angiograms in four children with sickle cell disease.
Volume
227
Issue
2
First Page
567
Last Page
574
ISSN
0033-8419
Published In/Presented At
Oguz, K. K., Golay, X., Pizzini, F. B., Freer, C. A., Winrow, N., Ichord, R., Casella, J. F., van Zijl, P. C., & Melhem, E. R. (2003). Sickle cell disease: continuous arterial spin-labeling perfusion MR imaging in children. Radiology, 227(2), 567–574. https://doi.org/10.1148/radiol.2272020903
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
12663827
Department(s)
Department of Pediatrics
Document Type
Article