Moyamoya syndrome associated with Alagille syndrome: outcome after surgical revascularization.

Authors

Lissa C Baird
Edward R Smith
Rebecca Ichord
David A Piccoli
Timothy J Bernard
Nancy B Spinner
R Michael Scott
Binita M Kamath

Publication/Presentation Date

2-1-2015

Abstract

Vasculopathy is well-described in Alagille syndrome (ALGS); however, few data exist regarding neurosurgical interventions. We report 5 children with ALGS with moyamoya who underwent revascularization surgery. Postsurgical complications included 1 stroke and 1 death from thalamic hemorrhage. Global function improved in survivors. Revascularization is reasonably safe in patients with ALGS and may improve neurologic outcomes.

Volume

166

Issue

2

First Page

470

Last Page

473

ISSN

1097-6833

Published In/Presented At

Baird, L. C., Smith, E. R., Ichord, R., Piccoli, D. A., Bernard, T. J., Spinner, N. B., Scott, R. M., & Kamath, B. M. (2015). Moyamoya syndrome associated with Alagille syndrome: outcome after surgical revascularization. The Journal of pediatrics, 166(2), 470–473. https://doi.org/10.1016/j.jpeds.2014.10.067

Disciplines

Medicine and Health Sciences | Pediatrics

PubMedID

25465847

Department(s)

Department of Pediatrics

Document Type

Article