Advances in big data and omics: Paving the way for discovery in childhood epilepsies.
Publication/Presentation Date
8-1-2024
Abstract
The insights gained from big data and omics approaches have transformed the field of childhood genetic epilepsy. With an increasing number of individuals receiving genetic testing for seizures, we are provided with an opportunity to identify clinically relevant subgroups and extract meaningful observations from this large-scale clinical data. However, the volume of data from electronic medical records and omics (e.g., genomics, transcriptomics) is so vast that standardized methods, such as the Human Phenotype Ontology, are necessary for reliable and comprehensive characterization. Here, we explore the integration of clinical and omics data, highlighting how these approaches pave the way for discovery in childhood epilepsies.
Volume
54
Issue
8
First Page
101634
Last Page
101634
ISSN
1538-3199
Published In/Presented At
Magielski, J., McSalley, I., Parthasarathy, S., McKee, J., Ganesan, S., & Helbig, I. (2024). Advances in big data and omics: Paving the way for discovery in childhood epilepsies. Current problems in pediatric and adolescent health care, 54(8), 101634. https://doi.org/10.1016/j.cppeds.2024.101634
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
38825428
Department(s)
Department of Pediatrics
Document Type
Article