Factors associated with treatment delays in pediatric refractory convulsive status epilepticus.
Publication/Presentation Date
5-8-2018
Abstract
OBJECTIVE: To identify factors associated with treatment delays in pediatric patients with convulsive refractory status epilepticus (rSE).
METHODS: This prospective, observational study was performed from June 2011 to March 2017 on pediatric patients (1 month to 21 years of age) with rSE. We evaluated potential factors associated with increased treatment delays in a Cox proportional hazards model.
RESULTS: We studied 219 patients (53% males) with a median (25th-75th percentiles [p
CONCLUSION: Intermittent rSE and out-of-hospital rSE onset are independently associated with longer delays to administration of the first BZD and the first non-BZD AED in pediatric rSE. These factors identify potential targets for intervention to reduce time to treatment.
Volume
90
Issue
19
First Page
1692
Last Page
1692
ISSN
1526-632X
Published In/Presented At
Sánchez Fernández, I., Gaínza-Lein, M., Abend, N. S., Anderson, A. E., Arya, R., Brenton, J. N., Carpenter, J. L., Chapman, K. E., Clark, J., Gaillard, W. D., Glauser, T. A., Goldstein, J. L., Goodkin, H. P., Helseth, A. R., Jackson, M. C., Kapur, K., Lai, Y. C., McDonough, T. L., Mikati, M. A., Nayak, A., … Pediatric Status Epilepticus Research Group (pSERG) (2018). Factors associated with treatment delays in pediatric refractory convulsive status epilepticus. Neurology, 90(19), e1692–e1701. https://doi.org/10.1212/WNL.0000000000005488
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
29643084
Department(s)
Department of Pediatrics
Document Type
Article