Validation of the Postnatal Growth and Retinopathy of Prematurity (G-ROP) criteria in a Slovenian cohort.

Publication/Presentation Date

2-1-2025

Abstract

PURPOSE: To validate the Postnatal Growth and ROP (G-ROP) study criteria for retinopathy of prematurity (ROP) screening in a Slovenian cohort.

METHODS: We conducted a retrospective cohort study of preterm infants screened in 2021 at the University Medical Centre Ljubljana, Slovenia. The G-ROP criteria were systematically applied. Primary outcomes were sensitivity for ROP requiring treatment, sensitivity for any ROP, and reduction in the number of infants screened.

RESULTS: Of 102 infants screened, 27 (26.4%) developed ROP. Eleven infants (10.7%) had type 1 ROP, of whom 2 (1.9%) had aggressive ROP; 5 infants (4.9%) had type 2 ROP, and 11 (10.7%) had milder ROP. Using the original or simplified G-ROP criteria, all infants who developed type 1 ROP (sensitivity, 100% [95% CI, 74%-100%]), and all infants who developed ROP (sensitivity, 100% [95% CI, 88%-100%]) were correctly identified. Application of the original G-ROP criteria would have reduced the number of infants screened by 29.4% (30 of 102).

CONCLUSIONS: In our cohort, both the original and simplified G-ROP criteria showed 100% sensitivity for predicting ROP type 1 while reducing the number of unnecessary screenings. These results confirm the reliability of the G-ROP criteria in the Slovenian context and suggest that their use improves screening efficiency.

Volume

29

Issue

1

First Page

104113

Last Page

104113

ISSN

1528-3933

Disciplines

Medicine and Health Sciences | Pediatrics

PubMedID

39863267

Department(s)

Department of Pediatrics

Document Type

Article

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