Postnatal weight gain and retinopathy of prematurity.
Publication/Presentation Date
10-1-2019
Abstract
Infants meeting retinopathy of prematurity (ROP) screening guidelines based on birth weight and gestational age undergo serial examinations by ophthalmologists for detection and treatment. However, less than 10% require treatment, and less than half develop ROP. Slow postnatal weight gain is highly predictive of ROP, and investigators have incorporated weight gain measures to develop more specific criteria for ROP screening. Such clinical prediction model use involves a large development study, validation studies specific to the target populations, and ongoing impact surveillance, with adjustment as necessary. Of the many weight gain inclusive prediction models intended to improve the precision of ROP screening, the Postnatal Growth and ROP (G-ROP) modified screening criteria were developed using the largest dataset and may provide the most robust model for clinical use. A recently completed G-ROP validation study will evaluate the generalizability of these modified criteria prior to clinical use.
Volume
43
Issue
6
First Page
352
Last Page
359
ISSN
1558-075X
Published In/Presented At
Lin, L., & Binenbaum, G. (2019). Postnatal weight gain and retinopathy of prematurity. Seminars in perinatology, 43(6), 352–359. https://doi.org/10.1053/j.semperi.2019.05.008
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
31221520
Department(s)
Department of Pediatrics
Document Type
Article