Late recurrence of retinopathy of prematurity after treatment with both intravitreal bevacizumab and laser.

Publication/Presentation Date

8-1-2014

Abstract

An infant of 36 weeks' postmenstrual age (PMA) and 25 weeks' gestation received bilateral intravitreal bevacizumab injections for type 1 retinopathy of prematurity. He underwent laser photocoagulation in both eyes 5 days later, confluent except for 1 clock hour obscured by hemorrhage in the left eye. Despite initial regression, neovascularization in both vascularized and lasered retina with plus disease recurred, requiring repeat laser bilaterally at 51 weeks' PMA and vitrectomy in the left eye at 54 weeks' PMA. Whereas late recurrence is thought to occur rarely after laser treatment, infants who have received both bevacizumab injections and laser may still require long-term surveillance for recurrence. In this case, fundus photography proved valuable for appreciating recurrent plus disease because the initial treatments had resulted in marked retinal vessel attenuation.

Volume

18

Issue

4

First Page

402

Last Page

404

ISSN

1528-3933

Disciplines

Medicine and Health Sciences | Pediatrics

PubMedID

25087645

Department(s)

Department of Pediatrics

Document Type

Article

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