Prevalence of risk of deficiency and inadequacy of 25-hydroxyvitamin D in US children: NHANES 2003-2006.
AIM: To assess prevalence and population estimates of increased risk of 25-hydroxyvitamin D [25(OH)D] deficiency and inadequacy in US children based on the current Institute of Medicine Committee to Review Dietary References Intakes for Vitamin D and Calcium guidelines.
METHODS: The analysis was limited to a nationally representative sample of non-institutionalized US children and adolescents aged 6-18 years who participated in the National Health and Nutrition Examination Survey completed in 2003-2006 and had complete data on 25(OH)D measurements (n=2877). The 25(OH)D levels were adjusted for assay drift and prevalence, and population estimates of increased risk of 25(OH)D deficiency (/mL), risk of inadequacy (/mL), and adequacy (>20 ng/mL) were calculated.
RESULTS: Overall, 4.61% of children and adolescents are at increased risk of deficiency (population estimate 2.5 million) and 10.3% are at risk of inadequacy (population estimate 5.5 million) based on the Institute of Medicine guidelines.
CONCLUSION: Approximately 10.3% of US children aged 6-18 years (population estimate 5.5 million) have 25(OH)D levels/mL.
Published In/Presented At
Karalius, V. P., Zinn, D., Wu, J., Cao, G., Minutti, C., Luke, A., … Durazo-Arvizu, R. (2014). Prevalence of risk of deficiency and inadequacy of 25-hydroxyvitamin D in US children: NHANES 2003-2006. Journal Of Pediatric Endocrinology & Metabolism: JPEM, 27(5–6), 461–466. https://doi.org/10.1515/jpem-2013-0246
Medicine and Health Sciences | Pediatrics
Department of Pediatrics