Chronically Implanted Intracranial Electrodes: Tissue Reaction and Electrical Changes.
Publication/Presentation Date
8-25-2018
Abstract
The brain-electrode interface is arguably one of the most important areas of study in neuroscience today. A stronger foundation in this topic will allow us to probe the architecture of the brain in unprecedented functional detail and augment our ability to intervene in disease states. Over many years, significant progress has been made in this field, but some obstacles have remained elusive-notably preventing glial encapsulation and electrode degradation. In this review, we discuss the tissue response to electrode implantation on acute and chronic timescales, the electrical changes that occur in electrode systems over time, and strategies that are being investigated in order to minimize the tissue response to implantation and maximize functional electrode longevity. We also highlight the current and future clinical applications and relevance of electrode technology.
Volume
9
Issue
9
ISSN
2072-666X
Published In/Presented At
Campbell, A., & Wu, C. (2018). Chronically Implanted Intracranial Electrodes: Tissue Reaction and Electrical Changes. Micromachines, 9(9), 430. https://doi.org/10.3390/mi9090430
Disciplines
Medicine and Health Sciences
PubMedID
30424363
Department(s)
Department of Surgery
Document Type
Article