Diffusion tensor imaging and fiber-tracking in Marchiafava-Bignami disease.
Publication/Presentation Date
7-1-2006
Abstract
Marchiafava-Bignami disease, a rare disorder most commonly seen in patients with a history of alcohol consumption, involves demyelination and subsequent necrosis of the corpus callosum. Diffusion tensor imaging demonstrates regional abnormalities in the corpus callosum that are not evident by conventional magnetic resonance imaging (MRI). Furthermore, fiber-tracking demonstrates significant disruption of axonal fiber bundles within the corpus callosum, most marked within the body, corresponding to the clinical finding of interhemispheric disconnection, which is characteristic of the disease.
Volume
16
Issue
3
First Page
281
Last Page
285
ISSN
1051-2284
Published In/Presented At
Sair, H. I., Mohamed, F. B., Patel, S., Kanamalla, U. S., Hershey, B., Hakma, Z., & Faro, S. H. (2006). Diffusion tensor imaging and fiber-tracking in Marchiafava-Bignami disease. Journal of neuroimaging : official journal of the American Society of Neuroimaging, 16(3), 281–285. https://doi.org/10.1111/j.1552-6569.2006.00041.x
Disciplines
Medicine and Health Sciences
PubMedID
16808832
Department(s)
Department of Surgery
Document Type
Article