Early and late basilar artery thrombectomy time window outcomes.
Publication/Presentation Date
1-1-2024
Abstract
IMPORTANCE: Stroke-to-recanalization time is a strong predictor of outcomes in anterior circulation large-vessel occlusion (LVO). The authors aimed to evaluate functional outcomes in early (< 6 h) vs. late (6-24 h) time windows for thrombectomy-treated basilar artery occlusions.
METHODS: Patients were derived from the Posterior Circulation Ischemic Stroke Evaluation: Analyzing Radiographic and Intra-procedural Predictors of Mechanical Thrombectomy (PC-SEARCH) Registry and retrospectively analyzed early and late basilar artery thrombectomy time windows cohorts. Patients were dichotomized based on the last known well and correlated to 90-day functional outcomes (mRS 0-3). A multiple logistic regression analysis was performed.
RESULTS: A total of 405 patients were included in this study: 216 and 189 patients in the early and late time windows, respectively. Baseline demographic, stroke, radiographic, and intraprocedural characteristics were similar between the groups. A total of 99 (46%) and 79 (42%) patients in the early and late time windows, respectively, achieved favorable functional outcomes at 90 days (
CONCLUSION: The early and late thrombectomy time windows can achieve similar rates of 90-day favorable functional outcomes. However, timely thrombectomy influences the likelihood of achieving excellent functional outcomes (mRS ≤ 2) within the early time window.
Volume
15
First Page
1352310
Last Page
1352310
ISSN
1664-2295
Published In/Presented At
Mierzwa, A. T., Rao, R., Al Kasab, S., Nelson, A., Ortega-Gutierrez, S., Vivanco-Suarez, J., Farooqui, M., Jadhav, A. P., Desai, S., Toth, G., Alrohimi, A., Nguyen, T. N., Klein, P., Abdalkader, M., Salahuddin, H., Pandey, A., Wilseck, Z., Koduri, S., Vora, N., Aladamat, N., … Jumaa, M. (2024). Early and late basilar artery thrombectomy time window outcomes. Frontiers in neurology, 15, 1352310. https://doi.org/10.3389/fneur.2024.1352310
Disciplines
Medicine and Health Sciences
PubMedID
38343711
Department(s)
Department of Surgery
Document Type
Article