Intramedullary Amputation Neuromas Associated with Spinal Ependymomas.
We report 5 spinal intramedullary masses containing combined ependymoma and traumatic neuroma. The ependymomas, grade II "cellular" types, were intermixed with or separate from wavy, vaguely fascicular tissue that contained multiple axons immunoreactive for neurofilament protein. The neuromas presumably arose from small perivascular nerve twigs that have been implicated in the pathogenesis of intramedullary neuromas in non-neoplastic spinal diseases. Pathologists should be aware of this distinctive intramedullary tissue that is not to be confused with a neoplasm.
Published In/Presented At
Johnson, M. W., & Burger, P. C. (2009). Intramedullary amputation neuromas associated with spinal ependymomas. The American Journal Of Surgical Pathology, 33(4), 639-643. doi:10.1097/PAS.0b013e31818fe3c9
Medical Pathology | Pathology
Peer Reviewed for front end display
Department of Pathology and Laboratory Medicine