USF-LVHN SELECT

A Case Report on Aggressive Natural Killer Cell Leukemia in a Pediatric Patient.

Publication/Presentation Date

6-1-2022

Abstract

Aggressive natural killer cell leukemia (ANKL) is a rare neoplastic malignancy, especially in pediatric populations with very few cases reported in the literature. It commonly presents with a rapidly declining clinical course and has a median survival of two months. We report the case of a 15-year-old female who presented with fever, hepatosplenomegaly, hemophagocytosis, and disseminated intravascular coagulation (DIC). The patient was ultimately diagnosed with ANKL but died after developing multiorgan failure and DIC prior to the initiation of any treatment. In this case report, we review and discuss the literature concerning the diagnosis and treatment of ANKL in pediatric patients.

Volume

14

Issue

6

First Page

25634

Last Page

25634

ISSN

2168-8184

Disciplines

Medical Education | Medicine and Health Sciences

PubMedID

35795499

Department(s)

USF-LVHN SELECT Program, USF-LVHN SELECT Program Students

Document Type

Article

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