Potential Impact on Clinical Decision Making via a Genome-Wide Expression Profiling: A Case Report.
Publication/Presentation Date
11-1-2016
Abstract
Management of men with prostate cancer is fraught with uncertainty as physicians and patients balance efficacy with potential toxicity and diminished quality of life. Utilization of genomics as a prognostic biomarker has improved the informed decision-making process by enabling more rationale treatment choices. Recently investigations have begun to determine whether genomic information from tumor transcriptome data can be used to impact clinical decision-making beyond prognosis. Here we discuss the potential of genomics to alter management of a patient who presented with high-risk prostate adenocarcinoma. We suggest that this information help selecting patients for advanced imaging, chemotherapies, or clinical trial.
Volume
9
First Page
51
Last Page
54
ISSN
2214-4420
Published In/Presented At
Kim, H., Alshalalfa, M., Hoffman-Censits, J., Lallas, C. D., Davicioni, E., Lin, J., Birbe, R., Erho, N., Lehrer, J., Ashab, H. A., Takhar, M., Olson, A., Lam, L. L., Kelly, W. K., Knudsen, K. E., Thangavel, C., Seiler, R., Feng, F. Y., Schaeffer, E. M., Trabulsi, E. J., … Den, R. B. (2016). Potential Impact on Clinical Decision Making via a Genome-Wide Expression Profiling: A Case Report. Urology case reports, 9, 51–54. https://doi.org/10.1016/j.eucr.2016.08.010
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
27713863
Department(s)
Administration and Leadership
Document Type
Article