Comparison of lymph node yield in robot-assisted laparoscopic prostatectomy with that in open radical retropubic prostatectomy.

Authors

• Costas D Lallas
• Mark L Pe
• Adeep B Thumar
• Thenappan Chandrasekar
• Franklin C Lee
• Peter McCue
• Leonard G Gomella
• Edouard J Trabulsi

Publication/Presentation Date

4-1-2011

Abstract

OBJECTIVE: • To investigate both the feasibility and the adequacy of pelvic lymph node dissection (PLND) during robot-assisted laparoscopic prostatectomy (RALP) by comparing lymph node yields obtained during RALP with those obtained during traditional open retropubic radical prostatectomy (RRP).

PATIENTS AND METHODS: • We retrospectively reviewed 1047 patients who underwent radical prostatectomy between 2001 and 2009. • In all, 626 patients underwent RALP while 421 patients had traditional open RRP. All patients undergoing bilateral PLND were included in our analysis. • Lymph node yields and lymph node involvement for each surgical approach were calculated and examined. • PLND-related complications were analysed.

RESULTS: • Of the 1047 patients, 816 patients underwent bilateral PLND of whom 473 underwent RALP, while 343 underwent RRP. The mean lymph node yields for the RALP cohort (7.1, interquartile range 4-10) was significantly higher (P < 0.001) than for the RRP cohort (6.0, interquartile range 3-8). • The percentage of patients with nodal involvement was 1.1 for RALP and 2.3 for RRP (P= 0.167). • Mean age, preoperative PSA values, and pre- and postoperative Gleason scores were similar between the two cohorts. • PLND-related complications were similar between both cohorts.

CONCLUSIONS: • In patients undergoing RALP, PLND is feasible and provides lymph node yields comparable with those of the standard open approach. • PLND should be strongly considered in all radical prostatectomy patients when clinically indicated, regardless of surgical technique.

Volume

107

Issue

7

First Page

1136

Last Page

1140

ISSN

1464-410X

Published In/Presented At

Lallas, C. D., Pe, M. L., Thumar, A. B., Chandrasekar, T., Lee, F. C., McCue, P., Gomella, L. G., & Trabulsi, E. J. (2011). Comparison of lymph node yield in robot-assisted laparoscopic prostatectomy with that in open radical retropubic prostatectomy. BJU international, 107(7), 1136–1140. https://doi.org/10.1111/j.1464-410X.2010.09621.x

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

20825403

Department(s)

Administration and Leadership

Document Type

Article