Re: identification of patients with prostate cancer who benefit from immediate postoperative radiotherapy: EORTC 22911.
Publication/Presentation Date
4-1-2008
Abstract
In EORTC22911, 1005 patients with pT3 prostate cancer following radical prostatectomy were randomized to observation or immediate postoperative adjuvant radiotherapy [1]. Van der Kwast performed a pathologic analysis of EORTC22911 using the radical prostatectomy specimens from 552 study patients. Patients with negative surgical margins had no benefit from postoperative radiotherapy. However, with positive margins, the hazard ratio for prostate-specific antigen (PSA) relapse was 0.38 for those receiving radiation compared with those who did not. Adjuvant radiation would prevent biochemical relapse by year 5 in 291 of every 1000 patients with positive margins compared with 88 of 1000 patients with negative margins.
Volume
53
Issue
4
First Page
855
Last Page
856
ISSN
0302-2838
Published In/Presented At
Gomella L. G. (2008). Re: identification of patients with prostate cancer who benefit from immediate postoperative radiotherapy: EORTC 22911. European urology, 53(4), 855–856. https://doi.org/10.1016/j.eururo.2008.01.039
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
18441534
Department(s)
Administration and Leadership
Document Type
Article