Evaluation of hemolysis in patients with prosthetic heart valves.

Publication/Presentation Date

6-1-1998

Abstract

The primary mechanism and most common cause of hemolytic disease in patients with prosthetic heart valves are mechanical trauma to red blood cells and paraprosthetic valvular regurgitation, respectively. Presenting features in patients with this condition include anemia, congestive heart failure, fatigue, jaundice, dark urine, and a regurgitant murmur. Various laboratory studies can be utilized to diagnose hemolytic anemia and to assess the severity of hemolysis. Transthoracic echocardiography, transesophageal echocardiography, and Doppler studies including color Doppler are useful imaging methods to assess valve function. Treatment is usually medical (oral iron); however, in patients with paravalvular regurgitation, surgery is often required to correct the anemia.

Volume

21

Issue

6

First Page

387

Last Page

392

ISSN

0160-9289

Disciplines

Medicine and Health Sciences

PubMedID

9631266

Department(s)

Department of Medicine, Cardiology Division

Document Type

Article

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