Oral anticoagulation in patients with cardiomyopathy or heart failure in sinus rhythm.

Authors

P PullicinoFollow
J L P ThompsonFollow
J P MohrFollow
R L SaccoFollow
Ronald S. Freudenberger MD, Lehigh Valley Health NetworkFollow
B LevinFollow
S HommaFollow

Publication/Presentation Date

1-1-2008

Abstract

BACKGROUND: Despite many prospective randomized studies defining the benefits of anticoagulation in atrial fibrillation (AF), there have been no adequate studies in cardiomyopathy (CM) in sinus rhythm.

METHODS: We review the current knowledge of the risk of stroke in CM, left ventricular systolic dysfunction and heart failure as well as the indications for antithrombotic agents and compare this with AF.

RESULTS: The current knowledge of risk factors for stroke and indications for antithrombotic agents in CM is similar to that of AF prior to the treatment studies of the 1980s-1990s.

CONCLUSION: Prospective randomized trial data are urgently needed to determine the role of antithrombotic drugs in CM.

Volume

26

Issue

3

First Page

322

Last Page

327

ISSN

1421-9786

Published In/Presented At

Pullicino, P., Thompson, J. L., Mohr, J. P., Sacco, R. L., Freudenberger, R., Levin, B., & Homma, S. (2008). Oral anticoagulation in patients with cardiomyopathy or heart failure in sinus rhythm. Cerebrovascular diseases (Basel, Switzerland), 26(3), 322–327. https://doi.org/10.1159/000149581

Disciplines

Medicine and Health Sciences

PubMedID

18667814

Department(s)

Cardiology Division

Document Type

Article