Title

Pharmacologic management of chronic reno-cardiac syndrome.

Publication/Presentation Date

3-1-2013

Abstract

Chronic kidney disease (CKD) significantly increases cardiovascular morbidity and mortality. CKD remains an under-represented population in cardiovascular clinical trials, and cardiovascular disease is an under-treated entity in CKD. Traditional cardiovascular risk factors in conjunction with uremia-related complications often progress to myocardial dysfunction. Such uremic cardiomyopathy leads to over-activation of neurohormonal pathways with detrimental effects. Management of the reno-cardiac syndrome (RCS) requires the targeting of these multiple facets. In this article we discuss the relevant pathophysiology of RCS, and present the clinical data related to its management.

Volume

10

Issue

1

First Page

54

Last Page

62

ISSN

1546-9549

Disciplines

Medicine and Health Sciences

PubMedID

23143732

Department(s)

Department of Medicine, Cardiology Division

Document Type

Article

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