Mechanical Valve Thrombosis in a Pregnant Patient: A Case of Therapeutic Failure.
Mechanical valve thrombosis is life-threatening complication especially in pregnant patients. The optimal anticoagulation regimen is still not certain as there are different fetal and maternal risks associated with anticoagulation. A 37-year-old woman with a history of rheumatic heart disease with a mechanical mitral valve replacement 13 years prior presented to the hospital with dyspnea on mild exertion associated with orthopnea for three days. She was nine weeks pregnant, she had been on warfarin prior to pregnancy, and was switched to low molecular weight heparin (LMWH) in her 6th week of pregnancy. Fluoroscopy showed that one leaflet of the mitral valve was nearly fixed, while the other leaflet had restricted motion at maximal opening. Transesophageal echocardiogram (TEE) showed a very large thrombus approximately 3-4 cm
Published In/Presented At
Gupta, R., Ranchal, P., & Harburger, J. (2019). Mechanical Valve Thrombosis in a Pregnant Patient: A Case of Therapeutic Failure. Cureus, 11(9), e5615. https://doi.org/10.7759/cureus.5615
Medicine and Health Sciences
Department of Medicine, Cardiology Division, Fellows and Residents