Biotic therapies for irritable bowel syndrome: current interventions.

Authors

• Gina Wodarczyk
• Maria Winte
• Diana Mastellone
• Termen Singh
• Joshua DeSipio
• Sangita Phadtare

Publication/Presentation Date

2-1-2026

Abstract

Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder characterized by recurrent abdominal pain and changes in bowel habits without measurable disease processes. Recent research emphasizes the gut-brain-microbiome (GBM) axis and explores how microbiota influence gastrointestinal and central nervous system functions. Here, we first discuss a brief overview of various treatment approaches for IBS, focusing on interventions such as probiotics, prebiotics, or synbiotics that target the GBM axis in adults with IBS. Relevant trials discussed the use of probiotics, prebiotics, or synbiotics.

Volume

14

First Page

062

Last Page

062

ISSN

2052-0034

Published In/Presented At

Wodarczyk, G., Winte, M., Mastellone, D., Singh, T., DeSipio, J., & Phadtare, S. (2026). Biotic therapies for irritable bowel syndrome: current interventions. Gastroenterology report, 14, goag062. https://doi.org/10.1093/gastro/goag062

PubMedID

42445725

Department(s)

Medical Education

Document Type

Article