Sex as a Biological Variable in Emergency Medicine Research and Clinical Practice: A Brief Narrative Review.

Publication/Presentation Date

10-1-2017

Abstract

The National Institutes of Health recently highlighted the significant role of sex as a biological variable (SABV) in research design, outcome and reproducibility, mandating that this variable be accounted for in all its funded research studies. This move has resulted in a rapidly increasing body of literature on SABV with important implications for changing the clinical practice of emergency medicine (EM). Translation of this new knowledge to the bedside requires an understanding of how sex-based research will ultimately impact patient care. We use three case-based scenarios in acute myocardial infarction, acute ischemic stroke and important considerations in pharmacologic therapy administration to highlight available data on SABV in evidence-based research to provide the EM community with an important foundation for future integration of patient sex in the delivery of emergency care as gaps in research are filled.

Volume

18

Issue

6

First Page

1079

Last Page

1090

ISSN

1936-9018

Disciplines

Emergency Medicine

PubMedID

29085541

Department(s)

Department of Emergency Medicine, Department of Emergency Medicine Faculty

Document Type

Article

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