Management of diabetes in the elderly with canagliflozin: A newer hypoglycemic drug on the horizon.
Canagliflozin is the first available oral inhibitor of sodium/glucose cotransporter 2 (SGLT2) in the market. At the outset it sounds excellent for the use in the elderly diabetic population, because of its minimal tendency to cause hypoglycemia. However, the clinician needs to exercise caution as it needs to be dosed renally. The clinician needs to be circumspect about potential drug interactions, especially when there is an underlying chronic kidney disease (CKD) and congestive heart failure (CHF). Also its use is best avoided in people who are predisposed to genital mycotic and urinary tract infections (UTI).
Published In/Presented At
Sehgal, V., Bajwa, S. J., Sehgal, R., & Consalvo, J. A. (2014). Management of diabetes in the elderly with canagliflozin: A newer hypoglycemic drug on the horizon. Journal of pharmacology & pharmacotherapeutics, 5(4), 227–231. https://doi.org/10.4103/0976-500X.142428
Medicine and Health Sciences
Department of Emergency Medicine