Premature infants with gestational age less than 25 weeks require increased ophthalmology resources for retinopathy of prematurity.
BACKGROUND: It is unclear how increasing survival of low gestational age (GA) infants affects ophthalmologic screening and treatment rates for retinopathy of prematurity (ROP). This study compared the examination and treatment rates of infants born at GA ofweeks.
METHODS: This was a retrospective study of patients who met institutional ROP screening criteria and were admitted to two neonatal intensive care units (NICUs) from January 2017 to June 2020. Variables analyzed were GA, birth weight, number of ophthalmology examinations, worst stage of ROP, presence of type 1 ROP, and comorbidities associated with ROP. The χ
RESULTS: Compared to the GA≥25 group, the GA(10 vs 4.3 [P < 0.001]), higher average worst stage of ROP (1.4 vs 0.3 [P < 0.001]) and higher rate of type 1 ROP (21% vs 1.4% [P < 0.001]), as well as higher mortality (37% vs 8.11% [P < 0. 001]). Multivariable logistic regression analysis controlling for GA, sepsis, and number of transfusions revealed that only GA was significantly associated with developing type 1 ROP.
CONCLUSIONS: Infants with GA≥25. It is important for ROP services to plan for this increased screening load, especially if the number of such lower-weight infants in their NICUs increases.
Published In/Presented At
Hawn, V. S., Muhtadi, R., Suman, P., Latuga, M. S., Quinn, G., & Mian, U. (2022). Premature infants with gestational age less than 25 weeks require increased ophthalmology resources for retinopathy of prematurity. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 26(6), 307.e1–307.e5. https://doi.org/10.1016/j.jaapos.2022.09.007
Medicine and Health Sciences
Department of Emergency Medicine, Department of Emergency Medicine Residents, Fellows and Residents