Atrial fibrillation in hypertrophic cardiomyopathy: prevalence, clinical impact, and management.
Publication/Presentation Date
3-2019
Abstract
Hypertrophic cardiomyopathy (HCM) is the most common hereditary cardiomyopathy characterized by left ventricular hypertrophy and spectrum of clinical manifestation. Atrial fibrillation (AF) is a common sustained arrhythmia in HCM patients and is primarily related to left atrial dilatation and remodeling. There are several clinical, electrocardiographic (ECG), and echocardiographic (ECHO) features that have been associated with development of AF in HCM patients; strongest predictors are left atrial size, age, and heart failure class. AF can lead to progressive functional decline, worsening heart failure and increased risk for systemic thromboembolism. The management of AF in HCM patient focuses on symptom alleviation (managed with rate and/or rhythm control methods) and prevention of complications such as thromboembolism (prevented with anticoagulation). Finally, recent evidence suggests that early rhythm control strategy may result in more favorable short- and long-term outcomes.
Volume
24
Issue
2
First Page
189
Last Page
197
ISSN
1573-7322
Published In/Presented At
Garg, L. Gupta, M. Sabzwari, S. Agrawal, S. Agarwal, M. Nazir, T. Gordon, J. Bozorgnia, B. Martinez, M. (2018). Atrial fibrillation in hypertrophic cardiomyopathy: prevalence, clinical impact, and management. Heart failure reviews, 24(2),189-197. doi: 10.1007/s10741-018-9752-6.
Disciplines
Cardiology | Internal Medicine
PubMedID
30456592
Department(s)
Department of Medicine, Cardiology Division, Department of Medicine Faculty, Department of Medicine Fellows and Residents
Document Type
Article