Publication/Presentation Date

6-27-2020

Abstract

Inflammatory bowel diseases are a group of chronic diseases of the digestive tract of unknown origin. The etiology of IBD is multifactorial and involves interaction between genetic, environmental and immunological factors with oxidative stress being an inherent part of any one of them. Therefore, the redox equilibrium is crucial to maintain cell homeostasis in the gastrointestinal (GI) tract, which is constantly exposed to large numbers of commensal and pathological bacteria. Distortion of this homeostasis and increase in oxidative stress leads to the propagation of inflammation, mucosal injury in the GI tract and is associated with the development and exacerbation of IBD.

Volume

66

Issue

2

First Page

143

Last Page

150

ISSN

0032-5422

Disciplines

Medicine and Health Sciences

PubMedID

32700508

Department(s)

Department of Medicine

Document Type

Article

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