Neurobrucellosis in an endemic area of brucellosis.
Central nervous system involvement occurs less than 5% of patients with brucellosis. A prospective analysis of 73 patients with brucellosis identified 13 (17.8%) neurobrucellosis cases from February 2001 to May 2002. 10 patients had chronic meningitis and 3 acute meningitis. Two patients had only psychiatric disorders. Cranial nerve involvement was observed in 3 patients (6th, 7th and 8th nerves). Three patients had positive blood cultures and 3 others had positive cerebrospinal fluid (CSF) cultures. 12 patients had positive agglutination titres in CSF. All patients received antibiotic therapy with ceftriaxone, rifampicin and doxycycline initially, and after 1 month they were continued with rifampicin and doxycycline up to 4 months. All patients were completely cured. Hearing loss developed in 1 patient as a sequela.
Published In/Presented At
Bodur, H., Erbay, A., Akinci, E., Colpan, A., Cevik, M. A., & Balaban, N. (2003). Neurobrucellosis in an endemic area of brucellosis. Scandinavian journal of infectious diseases, 35(2), 94–97. https://doi.org/10.1080/0036554021000027000
Medicine and Health Sciences
Department of Medicine