The utility of aspartate aminotransferase/platelet ratio index in HIV/hepatitis C-co-infected patients.
Liver biopsy is currently the gold standard for determining the stage of liver fibrosis. There are risks associated with liver biopsy; therefore, surrogate markers to predict the severity of disease would be useful. We studied 50 patients with HIV/hepatitis C co-infection who had liver biopsies and determined that no patient with an aspartate aminotransferase/platelet ratio index (APRI) of 0.6 or less had stage F3 or F4 disease. The APRI is useful for excluding advanced disease in this patient population.
Published In/Presented At
Shastry, L., Wilson, T., Lascher, S., & Nord, J. A. (2007). The utility of aspartate aminotransferase/platelet ratio index in HIV/hepatitis C-co-infected patients. AIDS (London, England), 21(18), 2541–2543. https://doi.org/10.1097/QAD.0b013e3282f1fe59
Medicine and Health Sciences
Department of Medicine