Early laboratory values after liver transplantation are associated with anastomotic biliary strictures.

Publication/Presentation Date

2-28-2022

Abstract

BACKGROUNDS/AIMS: The aim of this study was to evaluate longitudinal changes of post-liver transplantation (LT) biliary anatomy and to assess the association of increased laboratory values after LT with the development of post-LT anastomotic biliary stricture (ABS).

METHODS: Adult deceased donor LT recipients from 2008 and 2019 were evaluated. ABS was defined after blinded review of endoscopic cholangiograms. Controls were patients who underwent LT for hepatocellular carcinoma who did not have any clinical or biochemical concerns for ABS.

RESULTS: Of 534 patients who underwent LT, 57 patients had ABS and 57 patients served as controls. On MRI, ABS patients had a narrower anastomosis (2.47 ± 1.32 mm vs. 3.38 ± 1.05 mm;

CONCLUSIONS: Elevation of laboratory values early after LT is associated with ABS formation.

Volume

26

Issue

1

First Page

76

Last Page

83

ISSN

2508-5859

Disciplines

Medicine and Health Sciences

PubMedID

35013006

Department(s)

Department of Medicine

Document Type

Article

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