Inflammatory bowel disease patient concerns and experiences on transition to home-based infusions during the COVID-19 pandemic.
BACKGROUND: In response to the COVID-19 pandemic, the CDC issued guidance advising patients and providers to adopt social distancing practices such as home-based infusions (H-BI).
METHODS: We performed a mixed methods evaluation to summarize perceptions, concerns, and experiences with H-BI among all inflammatory bowel disease patients 18-90 years of age who transitioned to home-based infliximab or vedolizumab infusions between March to July 2020 at a tertiary care center. Semi-structured interviews were conducted and analyzed using an iterative, inductive thematic approach. Baseline characteristics and outcome on safety, COVID-19 transmission, delays in infusions, and H-BI persistence were collected.
RESULTS: Of the 57 participants who transitioned to H-BI, 20 (33%) responded. Four major categories and six major themes related to expectations, experience, perceived safety, and logistical factors were identified. Initial perceptions were mixed, however these resolved. One patient developed COVID-19, one patient experienced an adverse event, 12 (21%) patients experienced an infusion delay, and 6 (11%) patients transitioned from H-BI.
DISCUSSION: Despite mixed initial perceptions, respondents had a positive experience with most respondents planning to continue H-BI after the pandemic resolves. Several real-world actionable barriers were identified related to scheduling, communication between stakeholders, and nursing quality. No major safety concerns were identified.
Published In/Presented At
Jacob, J., Aintabi, D., DeJonckheere, M., Cohen-Mekelburg, S. A., Allen, J. I., Irani, D. N., Fendrick, A. M., Waljee, A. K., Higgins, P. D. R., & Berinstein, J. A. (2022). Inflammatory bowel disease patient concerns and experiences on transition to home-based infusions during the COVID-19 pandemic. Research in social & administrative pharmacy : RSAP, 18(12), 4138–4143. https://doi.org/10.1016/j.sapharm.2022.06.009
Medicine and Health Sciences
Department of Medicine, Department of Medicine Fellows and Residents, Fellows and Residents