Antigenic "Hot- Spots" on the TSH Receptor Hinge Region.

Publication/Presentation Date

1-1-2018

Abstract

The TSH receptor (TSHR) hinge region was previously considered an inert scaffold connecting the leucine-rich ectodomain to the transmembrane region of the receptor. However, mutation studies have established the hinge region to be an extended hormone-binding site in addition to containing a region which is cleaved thus dividing the receptor into

Volume

9

First Page

765

Last Page

765

ISSN

1664-2392

Disciplines

Medicine and Health Sciences

PubMedID

30666231

Department(s)

Department of Medicine

Document Type

Article

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