Antigenic "Hot- Spots" on the TSH Receptor Hinge Region.
The TSH receptor (TSHR) hinge region was previously considered an inert scaffold connecting the leucine-rich ectodomain to the transmembrane region of the receptor. However, mutation studies have established the hinge region to be an extended hormone-binding site in addition to containing a region which is cleaved thus dividing the receptor into
Published In/Presented At
Sun, S., Summachiwakij, S., Schneck, O., Morshed, S. A., Ma, R., Latif, R., & Davies, T. F. (2019). Antigenic "Hot- Spots" on the TSH Receptor Hinge Region. Frontiers in endocrinology, 9, 765. https://doi.org/10.3389/fendo.2018.00765
Medicine and Health Sciences
Department of Medicine