[Chemokines and their receptors: 2 new actors in the physiopathology of HIV infection].
The discovery of two novel structures (CXCR4, CCR5) that act as HIV-1 coreceptors in target cells has allowed a better understanding of the virus-cell interaction. The recent discovery that chemokines interact with the same receptors as HIV-1 has shed light in the comprehension of the viral molecular biology and pathophysiology, setting the stage for new efforts aimed at blocking virus-cell interaction.
Published In/Presented At
Davaro, R. E., & Bottaro, E. (1998). Quimiokinas y sus receptors. Dos nuevos actores en la fisiopatología de la infección por HIV [Chemokines and their receptors: 2 new actors in the physiopathology of HIV infection]. Medicina, 58(1), 78–84.
Medicine and Health Sciences
Department of Medicine