Role of a cefoxitin-inducible beta-lactamase in a case of breakthrough bacteremia.
Development of resistance during therapy with cefamandole contributes to treatment failure. A simple cefoxitin disk test was recently described which detects a cefamandole-active inducible beta-lactamase not otherwise detectable with cefamandole as the inducer. A case of breakthrough Enterobacter bacteremia due to selection of a resistant subpopulation is reported in an immunocompromised patient. The use of this simple disk test in selected clinical cases is advocated.
Published In/Presented At
Beckwith, D. G., & Jahre, J. A. (1980). Role of a cefoxitin-inducible beta-lactamase in a case of breakthrough bacteremia. Journal of clinical microbiology, 12(4), 517–520. https://doi.org/10.1128/jcm.12.4.517-520.1980
Medicine and Health Sciences
Department of Medicine