Single-fraction palliative pelvic radiation therapy in gynecologic oncology: 1,000 rads.

Publication/Presentation Date

3-1-1984

Abstract

The management of the patient with advanced gynecologic malignancies presents multiple problems for the gynecologic and radiation oncologists involved in their care. When palliative management only is indicated, conventional treatment protocols occupy a significant portion of the patient's remaining life span, often times with associated morbidity. Single-fraction external radiation therapy, consisting of 1,000 rads to the whole pelvis, was used in 30 patients with advanced gynecologic malignancies to palliate locally advanced pelvic disease. Alleviation of symptoms and maintenance of a reasonable quality of life were obtained in all patients. No untoward acute side effects were observed. Thirteen patients are alive from 2 to 19 months after treatment, with a mean overall survival after treatment of 8.4 months. It is concluded that this regimen should be considered as the palliative therapy of choice for certain patients with advanced gynecologic malignancies.

Volume

148

Issue

5

First Page

701

Last Page

705

ISSN

0002-9378

Disciplines

Medicine and Health Sciences

PubMedID

6199977

Department(s)

Department of Obstetrics and Gynecology

Document Type

Article

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