Micropapillary Urothelial Carcinoma: A Clinicopathological Study of the Experience of One Academic Center
Background: Micropapillary variant of urothelial carcinoma (MPUC) is a rare UC variant. MPUC have been reported in the urinary bladder, ureter and renal pelvis. Its prognosis and treatment is controversial in the literature. Some studies showed the overall prognosis for MPUC is poor and suggest the early treatment with cystectomy. Whereas one study demonstrated that there is no considerable difference between micropapillary pattern positive and negative groups according to the progression rates in non-muscle-invasive and muscle-invasive groups. In this study, we tried to study the clinicopathological correlation of MPUC, particularly comparison to conventional urothelial carcinoma with same grades and same stages.
Design: 23 MPUC, 135 low grade (LG) and 92 high grade (HG) UC are retrieved. The tumor stage, lymphatic invasion and metastasis including lymph node and distant organs are evaluated. Clinical follow-up is up to 8 years.
Published In/Presented At
Zhu, B., Lin, X, Rohan, S., Zhong, M., Goyal, R., Gershbach, E., Yang, X. (2012) Micropapillary Urothelial Carcinoma: A Clinicopathological Study of the Experience of One Academic Center. Modern Pathology. 25 (Supplement 2): 257A
Medical Pathology | Pathology
Department of Pathology and Laboratory Medicine, Pathology Laboratory Medicine Faculty