Acoustomotive optical coherence elastography for measuring material mechanical properties.
Acoustomotive optical coherence elastography (AM-OCE), a dynamic and internal excitation optical coherence elastography technique, is reported. Acoustic radiation force was used for internal mechanical excitation, and spectral-domain optical coherence tomography was used for detection. Mechanical properties of gelatin tissue phantoms were measured by AM-OCE and verified using rheometry results. Measured mechanical properties including shear moduli and shear damping parameters of the gelatin samples double when their polymer concentration increases from 3% to 4%. Spectral analysis was also performed on the acquired data, which improved the processing speed by a factor of 5 compared with a least-square fitting approach. Quantitative measurement, microscale resolution, and remote excitation are the main features of AM-OCE, which make the technique promising for measuring biomechanical properties.
Published In/Presented At
Liang, X., Orescanin, M., Toohey, K. S., Insana, M. F., & Boppart, S. A. (2009). Acoustomotive optical coherence elastography for measuring material mechanical properties. Optics letters, 34(19), 2894–2896. https://doi.org/10.1364/OL.34.002894
Medicine and Health Sciences | Oncology
Department of Radiation Oncology